Genclarus
Look up a human gene or a genetic variant (rsID) and get a clear, cited explanation grounded in real biology.
A stored answer
Full record ↗Every sentence names the fields it was built from. This record is assembled deterministically — no model in the path — and rendered by the same components a live answer uses. One sentence per distinct ClinVar verdict, because the same variant is called something different depending on the condition.
NM_000130.4(F5):c.1601G>A (p.Arg534Gln)
rs6025 is a genetic variant located in the F5 gene. dbsnp · gene
In ClinVar, rs6025 is classified as Drug response (toxicity) for hormonal contraceptives for systemic use response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs6025 is classified as Pathogenic for Congenital factor V deficiency (2 review stars; last evaluated 2025-02-03). clinvar · classificationclinvar · review confidenceclinvar · assertion date
In ClinVar, rs6025 is classified as Risk factor for Ischemic stroke (0 review stars, germline; last evaluated 2006-06-15). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs6025 is classified as Uncertain significance for Susceptibility to severe coronavirus disease (COVID-19) due to an impaired coagulation process (0 review stars, germline; last evaluated 2021-06-29). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
+11 more sentences on the full record
ClinVar by condition
15 conditions- Drug response
hormonal contraceptives for systemic use response - Toxicity
germlineeval. 2021-03-24 - Pathogenic
Congenital factor V deficiency
eval. 2025-02-03 - Pathogenic
Thrombophilia due to activated protein C resistance (THPH2)
germlineeval. 2023-07-12 - Pathogenic
Factor V deficiency
germlineeval. 2020-03-04
+11 more on the full record
facts 5f13eb02a589a06a · retrieved 2026-08-03